Bio-Process Development & Improvement
 

Fermentation & Downstream Processing Optimization

Deltra Labs provides bio-process development and optimization services for industrial fermentation and downstream processing workflows. We support both the establishment of new production processes and the improvement of existing fermentation systems with a focus on scalability, robustness, and economic feasibility.
 

Based in the Netherlands, we collaborate with biotechnology companies across Europe to optimize microbial production workflows from laboratory development through small pilot-scale operations.
 

Fermentation Process Development

Our fermentation development activities include:

• Media optimization

• Feeding strategy development

• Process parameter optimization

• Oxygen transfer optimization

• Process robustness evaluation

• Scale-up assessment

• Fermentation troubleshooting

• Productivity and titer improvement

• convert and scale your shake-flask protocol in a robust bioreactor protocol
   

We develop fermentation strategies tailored to the biological and operational requirements of each production system.
 

Downstream Processing & Yield Optimization

Efficient downstream processing is essential for commercially viable bioprocesses. Deltra Labs supports optimization of:

• Product recovery workflows

• Clarification strategies

• Extraction approaches

• Purification process efficiency

• DSP yield improvement

• Process reproducibility

Our goal is to identify practical downstream strategies that support both technical performance and process scalability.
 

Productivity, Titer & Process Efficiency

Many industrial biotechnology projects encounter limitations in process efficiency during development or scale-up. We help identify and address bottlenecks affecting:

• Product titers

• Volumetric productivity

• Fermentation consistency

• Raw material utilization

• Recovery efficiency

• Overall process economics

Optimization strategies are designed around realistic industrial operating conditions and commercial feasibility.
 

Laboratory & Small Pilot-Scale Production

In addition to process optimization, Deltra Labs supports laboratory and small pilot-scale production campaigns, including generation of target compound samples at up to 10 L fermentation scale inhouse and pilot scale via partners.
 

These campaigns can support:

• Technical validation

• Customer sampling

• Analytical evaluation

• Early-stage commercial assessment

• Proof-of-concept demonstrations
   

Our objective is to help clients rapidly generate meaningful experimental and production data while establishing scalable process foundations.

Looking to improve an existing fermentation process or establish a new production workflow?
 

→ Contact Deltra Labs to discuss your bioprocess development project